A dogmatic Stalinist, Hoxha considered religion a divisive force and undertook an active campaign against religious institutions, despite the virtual absence of religious intolerance in Albanian society. The Agrarian Reform Law of August 1945, for example, nationalized most property of religious institutions, including the estates of monasteries, orders, and dioceses. Many clergy and believers were tried, tortured, and executed. All foreign Roman Catholic priests, monks, and nuns were expelled in 1946.

In January 1949, almost three years after the adoption of the first communist constitution, which guaranteed freedom of religion, the government issued a far-reaching Decree on Religious Communities. The law required that religious communities be sanctioned by the state, that they comply with "the laws of the state, law and order, and good customs," and that they submit all appointments, regulations, and bylaws for approval by the government. Even pastoral letters and parish announcements were subject to the approval of party officials. Religious communities or branches that had their headquarters outside the country, such as the Jesuit and Franciscan orders, were henceforth ordered to terminate their activities in Albania. Religious institutions were forbidden to have anything to do with the education of the young, because that had been made the exclusive province of the state. All religious communities were prohibited from owning real estate and from operating philanthropic and welfare institutions and hospitals.

Although there were tactical variations in Hoxha's approach to each of the major denominations, his overarching objective was the eventual destruction of all organized religion in Albania. In the late 1940s and 1950s, the regime achieved control over the Muslim faith by formalizing the split between the Sunni and Bektashi sects, eliminating all leaders who opposed Hoxha's policies, and exploiting those who were more tractable. Steps were also taken to purge all Orthodox clergy who did not yield to the demands of the regime, and to use the church as a means of mobilizing the Orthodox population behind government policies. The Roman Catholic Church, chiefly because it maintained close relations with the Vatican and was more highly organized than the Muslim and Orthodox faiths, became the principal target of persecution. Between 1945 and 1953, the number of priests was reduced drastically and the number of Roman Catholic churches was decreased from 253 to 100. All Catholics were stigmatized as fascists, although only a minority had collaborated with the Italian occupation authorities during World War II.

The campaign against religion peaked in the 1960s. Inspired by China's Cultural Revolution, Hoxha called for an aggressive cultural-educational struggle against "religious superstition" and assigned the antireligious mission to Albania's students. By May 1967, religious institutions had been forced to relinquish all 2,169 churches, mosques, cloisters, and shrines in Albania, many of which were converted into cultural centers for young people. As the litc18 iterary monthly Nendori reported the event, the youth had thus "created the first atheist nation in the world."

The clergy were publicly vilified and humiliated, their vestments taken and desecrated. Many Muslim mullahs and Orthodox priests buckled under and renounced their "parasitic" past. More than 200 clerics of various faiths were imprisoned, others were forced to seek work in either industry or agriculture, and some were executed or starved to death. The cloister of the Franciscan order in Shkodėr was set on fire, which resulted in the death of four elderly monks.

All previous decrees that had officially sanctioned the nominal existence of organized religion were annulled in 1967. Subsequently, the 1976 constitution banned all "fascist, religious, warmongerish, antisocialist activity and propaganda," and the penal code of 1977 imposed prison sentences of three to ten years for "religious propaganda and the production, distribution, or storage of religious literature." A new decree that in effect targeted Albanians with Christian names stipulated that citizens whose names did not conform to "the political, ideological, or moral standards of the state" were to change them. It was also decreed that towns and villages with religious names must be renamed. Thus, in the southern areas populated by ethnic Greeks, about ninety towns and places named after Greek Orthodox saints received secular names.

Hoxha's brutal antireligious campaign succeeded in eradicating formal worship, but some Albanians continued to practice their faith clandestinely, risking severe punishment. Individuals caught with Bibles, icons, or other religious objects faced long prison sentences. Parents were afraid to pass on their faith, for fear that their children would tell others. Officials tried to entrap practicing Christians and Muslims during religious fasts, such as Lent and Ramadan, by distributing dairy products and other forbidden foods in school and at work, and then publicly denouncing those who refused the food. Clergy who conducted secret services were incarcerated in 1980, a Jesuit priest was sentenced to "life until death" for baptizing his nephew's newborn twins.

Data as of April 1992